Will APPLES Hit a Ceiling?

Yield Potential of Sugar Beet – Have We Hit the Ceiling?

The yield of sugar beet has continuously increased in the past decades. The question arises, whether this progress will continue in the future. A key factor for increasing yield potential of the crop is breeding progress. It was related to a shift in assimilate partitioning in the plant toward more storage carbohydrates (sucrose), whereas structural carbohydrates (leaves, cell wall compounds) u...

(When) Will CMPs Hit the Power Wall?

Currently the power wall is one of the major obstacles chip industry is facing. At the same time processor architecture shifts towards chip multiprocessors (CMPs), which are believed to alleviate the power problem. In this paper we analyze the impact of the power wall on CMP design. As a case study we model a CMP consisting of Alpha 21264 cores, scaled to future technology nodes according to th...

A 2014 medical informatics perspective on clinical decision support systems: do we hit the ceiling of effectiveness?

OBJECTIVE To summarize recent research and propose a selection of best papers published in 2013 in the field of computer-based decision support in health care. METHOD Two literature reviews were performed by the two section editors from bibliographic databases with a focus on clinical decision support systems (CDSSs) and computer provider order entry in order to select a list of candidate bes...

The Balanced Budget Act of 1997: will hospitals take a hit on their PPS margins?

The most critical question when reading a meta-analysis report: Is it comparing apples with apples or apples with oranges?

OBJECTIVE While the number of meta-analyses published has increased recently, most of them have problems in the design, analysis, and/or presentation. An example of meta-analyses with a study selection bias is a meta-analysis of over 160,000 patients in 20 clinical trials, published in Eur Heart J in 2012 by van Vark, which concluded that the significant effect of renin-angiotensin-aldosterone ...